Ariana Boswell

All articles by Ariana Boswell

• New study examines SM burden from both patient and provider perspectives

  A first-of-its-kind study in Europe identified sources of disease burden as reported by patients with SM and their healthcare providers.

• Sarilumab does not improve quality of life in patients with indolent SM

  A clinical trial of 16 patients with indolent SM found that sarilumab does not significantly improve quality of life.

• Case report: Patient diagnosed with rare, aggressive form of SM

  A patient who was diagnosed with mast cell leukemia, a rare form of SM, experienced symptom relief with methylprednisolone treatment.

• Case report: Patient develops SM after germ cell tumor treatment

  A 9-year-old girl underwent a stem cell transplant after being diagnosed with SM following treatment for a germ cell tumor.

• Case report: Aortic valve replacement failure in patient with aggressive SM

  A case report describes a patient who experienced two failed transcatheter aortic valve replacements, likely related to her underlying SM.

• Duplex sequencing uncovers additional responders to avapritinib

  Duplex sequencing can reveal KIT mutations in a subset of patients with SM who do not have detectable mutations by ddPCR, a study found.

• Rare Disease Day: Why it matters and how to get involved

  Rare Disease Day 2025 aims to uplift the rare disease community and promote greater awareness.

• Case report: Patient with SM undergoes successful thyroidectomy

  A recent case report illustrated the need for thorough care to prevent adverse postoperative outcomes in patients with SM.

• Case report highlights complexity of diagnosing SM in children

  A case study illustrated the difficulty of diagnosing systemic mastocytosis (SM), particularly in children.

• Clinical trial to assess long-term safety of avapritinib to treat SM

  A new study is recruiting participants and will evaluate the safety of avapritinib in treating SM over a period of four years.