Leonardo Jaimes, MD

All articles by Leonardo Jaimes, MD

• Patient diagnosed with mast cell leukemia, the rarest form of SM

  A recent case report details a patient with mast cell leukemia (MCL), which authors state may be the rarest form of systemic mastocytosis (SM).

• Case report: SM patient successfully treated for osteoporosis

  A case of patient with osteoporosis and systemic mastocytosis (SM) has highlighted the treatments available and the need for more data.

• New study explains how systemic mastocytosis can affect the liver

  The cellular changes that occur in the liver of patients with systemic mastocytosis (SM) have been described in a recent study.

• Systemic mastocytosis presents challenges during heart surgery

  A recent report describes a patient with undiagnosed systemic mastocytosis who experienced unexpected complications during heart surgery.

• Case report: 2 patients without KIT mutations diagnosed with SM

  Two cases involving patients with systemic mastocytosis (SM) without KIT mutations (KIT negative) have been recently reported.

• Desensitization to isatuximab allergy possible in patients with ISM

  Desensitization to isatuximab allergy in patients with ISM appears possible, according to a recent report.

• Potential new therapy shows promising results in SM trial

  A clinical trial assessing the efficacy of bezuclastinib in improving SM symptoms in patients with SM has shown positive mid-stage results.

• Patient diagnosed with SM through routine colonoscopy

  A recent case report describes an asymptomatic patient with SM who was diagnosed after a routine colonoscopy.

• Case report shows novel disease presentation in SM patient

  A recently-published case report highlights the importance of adequate tissue sampling when evaluating for SM, researchers wrote.

• SM therapy shows promise in phase 2 trial

  New data shows over half of patients in a phase 2 study of an investigational SM therapy saw improvement in severe SM-associated symptoms.