News

Case report: 2 patients without KIT mutations diagnosed with SM

by Leonardo Jaimes, MD

Two cases involving patients with systemic mastocytosis (SM) without KIT mutations (KIT negative) have been recently reported.

Desensitization to isatuximab allergy possible in patients with ISM

by Leonardo Jaimes, MD

Desensitization to isatuximab allergy in patients with ISM appears possible, according to a recent report.
Potential new therapy shows promising results in SM trial

by Leonardo Jaimes, MD

A clinical trial assessing the efficacy of bezuclastinib in improving SM symptoms in patients with SM has shown positive mid-stage results.
Patient diagnosed with SM through routine colonoscopy

by Leonardo Jaimes, MD

A recent case report describes an asymptomatic patient with SM who was diagnosed after a routine colonoscopy.

Case report shows novel disease presentation in SM patient

by Leonardo Jaimes, MD

A recently-published case report highlights the importance of adequate tissue sampling when evaluating for SM, researchers wrote.
SM therapy shows promise in phase 2 trial

by Leonardo Jaimes, MD

New data shows over half of patients in a phase 2 study of an investigational SM therapy saw improvement in severe SM-associated symptoms.
Type 1 interferon autoantibodies not linked to development of SM

by Sheila Jacobs

Researchers of a recently-published study found autoantibodies to type I [IFN] do not affect the pathogenesis or manifestations of SM.