Duplex sequencing uncovers additional responders to avapritinib
Duplex sequencing can reveal KIT mutations in a subset of patients with SM who do not have detectable mutations by ddPCR, a study found.
Duplex sequencing can reveal KIT mutations in a subset of patients with SM who do not have detectable mutations by ddPCR, a study found.
Results from a recent study could support more accurate diagnosis and future therapies in indolent systemic mastocytosis.
As fire ants spread to more areas, people with SM face a greater risk of severe allergic reactions from fire ant stings.
Non-white patients with systemic mastocytosis appear to have a longer diagnostic journey and a greater disease burden than white patients.
Scientists observed differences in bone marrow mast cell characteristics across different mast cell disorders.
A clinical trial is testing avapritinib and decitabine to improve outcomes for patients with SM and an associated blood cancer.
Research shows a possible link between cold urticaria and cold-induced anaphylaxis with systemic mastocytosis.
Though patients with ISM have a normal life expectancy, they need more health care visits and medications than the general population.
The HARBOR study will compare elenestinib with a placebo and best supportive care to determine its effectiveness in treating ISM.
Because SM is a rare disorder, it is sometimes diagnosed incidentally during unrelated procedures.